Yea, absolutely. OpenCart 2.2.x.x bring a new method to change the theme. You have adopted an earlier method that's why you are facing this obstacle. Anyways just follow the steps,
- OpenCart Admin Panel
- Extensions > Themes
- Edit your desired store
- Choose theme directory
- Modify status to Enabled
That's it. In case you disabled all themes, the site will show Error: A theme has not been assigned to this store!